UCLA study identifies key factors shaping prenatal brain development

Scientists at UCLA have uncovered two major influences that regulate how the human brain forms before birth. They found that radial glia, the stem cells that generate much of the cerebral cortex, alter their behavior based on how they interpret developmental signals.

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The UCLA investigation centers on the prenatal construction of the cerebral cortex, the brain region responsible for higher cognitive functions. Radial glia serve as the primary stem cells that generate this vital tissue,